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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YAP1
All Species:
21.52
Human Site:
S127
Identified Species:
43.03
UniProt:
P46937
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46937
NP_006097.1
504
54462
S127
P
Q
H
V
R
A
H
S
S
P
A
S
L
Q
L
Chimpanzee
Pan troglodytes
XP_001151402
488
52729
S127
P
Q
H
V
R
A
H
S
S
P
A
S
L
Q
L
Rhesus Macaque
Macaca mulatta
XP_001096954
125
14040
Dog
Lupus familis
XP_536601
465
50351
P134
F
E
I
P
D
D
V
P
L
P
A
G
W
E
M
Cat
Felis silvestris
Mouse
Mus musculus
P46938
488
52365
S112
P
Q
H
V
R
A
H
S
S
P
A
S
L
Q
L
Rat
Rattus norvegicus
Q2EJA0
469
50483
S112
P
Q
H
V
R
A
H
S
S
P
A
S
L
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510207
422
46067
A109
P
D
D
V
P
L
P
A
G
W
E
M
A
K
T
Chicken
Gallus gallus
P46936
448
47804
S126
P
Q
H
V
R
A
H
S
S
P
A
S
L
Q
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001132952
442
48343
A110
T
S
M
G
P
A
N
A
P
P
Q
H
L
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q45VV3
418
46202
A109
P
A
P
S
H
S
R
A
N
S
A
D
S
T
Y
Honey Bee
Apis mellifera
XP_391844
511
54750
S146
V
A
H
P
R
A
H
S
S
P
A
S
L
Q
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
R174
G
H
S
T
S
S
T
R
N
H
S
T
S
H
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
21.4
77.9
N.A.
88.6
84.9
N.A.
75.5
78.9
N.A.
73.2
N.A.
20.4
28.5
N.A.
N.A.
Protein Similarity:
100
96.8
23.6
83.3
N.A.
92.6
88.8
N.A.
79.5
81.5
N.A.
78.9
N.A.
34.5
44.4
N.A.
N.A.
P-Site Identity:
100
100
0
13.3
N.A.
100
100
N.A.
13.3
100
N.A.
20
N.A.
13.3
73.3
N.A.
N.A.
P-Site Similarity:
100
100
0
33.3
N.A.
100
100
N.A.
26.6
100
N.A.
40
N.A.
33.3
73.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
0
59
0
25
0
0
67
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
9
9
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
0
9
0
0
9
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
9
0
0
0
0
9
0
0
9
0
0
0
% G
% His:
0
9
50
0
9
0
50
0
0
9
0
9
0
9
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% K
% Leu:
0
0
0
0
0
9
0
0
9
0
0
0
59
0
42
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
9
% M
% Asn:
0
0
0
0
0
0
9
0
17
0
0
0
0
0
0
% N
% Pro:
59
0
9
17
17
0
9
9
9
67
0
0
0
0
9
% P
% Gln:
0
42
0
0
0
0
0
0
0
0
9
0
0
50
17
% Q
% Arg:
0
0
0
0
50
0
9
9
0
0
0
0
0
9
0
% R
% Ser:
0
9
9
9
9
17
0
50
50
9
9
50
17
0
0
% S
% Thr:
9
0
0
9
0
0
9
0
0
0
0
9
0
9
9
% T
% Val:
9
0
0
50
0
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _